Fertility treatment

right up to success


Through their co-operation the IVF Centers Prof. Zech and GE Healthcare – global market leader in ultrasound technology are setting new clinical standards in ultrasound monitoring in reproductive medicine.

The scientific paper submitted for publication by the IVF Centers Prof. Zech has been published in the renowned international journal RBMonline (reference).

Kinderwunschbehandlung - Ultraschallaufnahme
Ultrasound scan of follicle

IVF treatment involves the stimulation of a woman’s ovaries by a regimen of fertility drugs to trigger the development of multiple egg cells. These oocytes are maturing within the follicles in the ovaries. During ovarian stimulation the attending gynecologist is monitoring follicle growth by ultrasound scan. This ultrasound monitoring aims at determining the optimal time for administering human chorionic gonadotropin to induce ovulation and at selecting the most suitable moment to retrieve the eggs from the ovary (follicle puncture).

To date, only 2-D ultrasound techniques were available to assess follicular volume which only provided an approximation of the real volume as well as the right moment for administering human chorionic gonadotropin (hCG). In co-operation with GE Healthcare, the market leader in ultrasound technology, we performed for the first time ever, a clinical evaluation of the novel 3D-based automated volume count “SonoAVCTM” for monitoring follicle growth.

A comparative study revealed that using 3D-transvaginal ultrasound (compared to 2D ultrasound techniques) led to a significantly higher number of mature oocytes during ovarian stimulation. The study assumes that the more objective, faster, more reliable and more precise SonoAVCTM technique more closely mirrors biological reality in comparison to using conventional 2D-transvaginal ultrasound. Due to this new technique the entire treatment procedure in terms of an enhanced quality management can be optimized in order to guarantee the quality standards for IVF treatments established by the European Union directive.

We recently presented our latest findings at Austria’s biggest congress for reproductive medicine and endocrinology (OEGRM, Saalfelden, 2009).

It could be demonstrated once again, that
  • Examination and evaluation are significantly less time consuming.
  • As to volume and quantity the results obtained by SonoAVCTM are by far more precise compared to those achieved by using conventional 2D-ultrasound.
  • The results are reproducible and can be compared at any time.

The most important finding, however, is reflected by the outcome: the patients monitored by SonoAVC during ovarian stimulation showed the following results:
  • The number of high quality (criteria according to L. Veek) egg cells on the day of egg-retrieval increased.
  • Fertilization-rate on day 1 (after IVF or ICSI resp. IMSI) could be considerably improved.
  • The number of blastocysts on day 5 did rise.



IVF Centers Prof. Zech
IVF Zech International - Partners
Tel.: +43 5574 44836
Tel.: +43 662 9010 5000
Tel.: +41 71 950 1580
Tel.: +423 237 6655
Czech Republic
Tel.: +42 0377 279 350
Tel.: +39 0473 270470
(providing scientific and technical expertise)
Nuova Ricerca
Rimini, Italien
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Lagos State, Nigeria
Meden Healthcare
Casablanca, Morocco